Safety and efficacy of add-on intra-arterial thrombolysis after intravenous thrombolysis and mechanical thrombectomy in patients with ischemic stroke and cerebral vessel occlusion
Triple treatment (IVT, EVT, and IAT) did not significantly improve clinical outcomes compared to IVT and EVT alone. However, TT was safe without signs of increased bleeding complications. TT should not be routinely used until further evidence verifies safety and substantiates a possible benefit in specific patient populations.
Authors
- Hagen B. Huttner (ORCID: https://orcid.org/0000-0002-0992-8871)
- Tobias Struffert (ORCID: https://orcid.org/0000-0002-8708-597X)
- André Worm (ORCID: https://orcid.org/0009-0005-1052-7855)
- Anne Mrochen (ORCID: https://orcid.org/0000-0003-0826-4089)
- Omar Alhaj Omar (ORCID: https://orcid.org/0009-0007-1932-4303)
- Patrick Schramm (ORCID: https://orcid.org/0000-0001-5158-6708)
- Christian Claudi (ORCID: https://orcid.org/0009-0009-9732-5218)
- Norma J. Diel (ORCID: https://orcid.org/0009-0008-7801-7722)
- Kai Bernhard Woelk
- Oliver Posner
Institutions
- Justus-Liebig-Universität Gießen (DE)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-05-30
- DOI
- https://doi.org/10.3389/fneur.2025.1560045
- Citations
- 1
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 1.35