Clinical features and prognostic analysis of 120 patients with oropharyngeal squamous cell carcinoma: a hospital-based real-world study
In North China's Shanxi Province, the incidence of HPV-associated OPSCC has surpassed that of OPSCC caused by smoking and alcohol use. p16-positive patients with primary tumors located in the soft palate and posterior pharyngeal wall have a poor prognosis, indicating that treatment de-escalation should be approached with caution. Traditional open surgical treatment, without consideration of HPV status, does not appear to benefit patients.
Authors
- Feifei Ma (ORCID: https://orcid.org/0000-0003-1321-5564)
- Rui Wang (ORCID: https://orcid.org/0000-0001-8108-1508)
- Shuxin Wen (ORCID: https://orcid.org/0000-0002-8377-2481)
- Dapeng Wang (ORCID: https://orcid.org/0000-0001-5810-1806)
- Zhilin Li (ORCID: https://orcid.org/0000-0003-4047-940X)
- Zhang Li (ORCID: https://orcid.org/0000-0002-0452-6662)
- Jing Wang (ORCID: https://orcid.org/0009-0005-3735-734X)
Institutions
- Shanxi Medical University (CN)
- Shanxi Provincial Cancer Hospital (CN)
- Cancer Hospital of Chinese Academy of Medical Sciences (CN)
- Shanxi Academy of Medical Sciences (CN)
- Shanxi Provincial People’s Hospital (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-05-30
- DOI
- https://doi.org/10.3389/fonc.2025.1533688
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00