Robotically Controlled Terahertz Probe for In Vivo Skin Evaluation: Imaging with the PicoBot

In this work, we demonstrate significant modifications to our robotically controlled terahertz (THz) sensing system, the "PicoBot," enabling it to perform in vivo imaging of skin rather than limiting it to single-point measurements. By integrating a robotic arm equipped with force-sensitive feedback control, we maintain consistent contact pressure between the probe and the skin surface throughout imaging. In conjunction with this hardware advancement, we introduce an accompanying image analysis pipeline that reduces noise and enhances repeatability across scans. These improvements allow for reliable intra- and inter-subject comparisons, a critical step toward the clinical utility of THz imaging. Our ultimate aim is to use THz imaging to detect skin cancer margins: this paper highlights progress towards this goal and skin evaluation in general.

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Publication Details

Journal
Journal of Infrared Millimeter and Terahertz Waves
Published
2025-05-30
DOI
https://doi.org/10.1007/s10762-025-01055-7
Citations
2
Primary Topic
Terahertz technology and applications
Type
article
Field-Weighted Citation Impact
1.46

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article

Robotically Controlled Terahertz Probe for In Vivo Skin Evaluation: Imaging with the PicoBot

Emma Pickwell‐MacPherson, Joseph Hardwicke, Brendan Page, Agrima Agarwal et al.
2 citations
Journal of Infrared Millimeter and Terahertz Waves
Terahertz technology and applications
1.46
article

Robotically Controlled Terahertz Probe for In Vivo Skin Evaluation: Imaging with the PicoBot

Emma Pickwell‐MacPherson, Joseph Hardwicke, Brendan Page, Agrima Agarwal, Anubhav Dogra, Arturo I. Hernandez‐Serrano, Jacob J. Young
article en
2 citations

Abstract

In this work, we demonstrate significant modifications to our robotically controlled terahertz (THz) sensing system, the "PicoBot," enabling it to perform in vivo imaging of skin rather than limiting it to single-point measurements. By integrating a robotic arm equipped with force-sensitive feedback control, we maintain consistent contact pressure between the probe and the skin surface throughout imaging. In conjunction with this hardware advancement, we introduce an accompanying image analysis pipeline that reduces noise and enhances repeatability across scans. These improvements allow for reliable intra- and inter-subject comparisons, a critical step toward the clinical utility of THz imaging. Our ultimate aim is to use THz imaging to detect skin cancer margins: this paper highlights progress towards this goal and skin evaluation in general.

Journal of Infrared Millimeter and Terahertz WavesVol. 46(6)
University Hospital Coventry (GB), Warwickshire Hospital (GB), University of Warwick (GB)
Cancer Research UK, Royal Society, University of Warwick, Engineering and Physical Sciences Research Council
Openalex Percentile: Top 17%
Terahertz technology and applications
1.46
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