Case Report: Streptococcus dysgalactiae ssp. dysgalactiae bloodstream infections in patients with breast cancer after radiotherapy and chemotherapy

Bloodstream infections are life-threatening conditions in patients with breast cancer, especially among older individuals. Although the most common risk factor in these patients with tumors is the use of severe neutropenia secondary to myelosuppressive chemotherapy and radiotherapy, other factors are possibly associated with the invasive pathogenicity of microorganisms, including <i>Streptococcus dysgalactiae</i>. <i>Streptococcus dysgalactiae</i> ssp. <i>dysgalactiae (SDSD)</i> has been considered both an environmental pathogen and a contagious pathogen. However, there have been few reports of bloodstream infections with SDSD in patients with breast cancer after radiotherapy and chemotherapy. In this study, we report an interesting case of bloodstream infection caused by SDSD in an older patient with breast cancer after radiotherapy and chemotherapy. A 60-year-old Chinese woman had a history of breast cancer for 2 years. She developed chills and fever after puncturing blood blisters in the mouth, accompanied by fatigue and poor appetite. After 6 days of antimicrobial therapy, the patient showed gradual recovery. Bloodstream infections with SDSD in patients with breast cancer are rare. Therefore, accurate diagnosis and timely treatment can be lifesaving.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-05-30
DOI
https://doi.org/10.3389/fmed.2025.1572998
Primary Topic
Streptococcal Infections and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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Case Report: Streptococcus dysgalactiae ssp. dysgalactiae bloodstream infections in patients with breast cancer after radiotherapy and chemotherapy

Jingbai Chen, Zhixin You, Chongmei Tian, Yaping Zhao et al.
Frontiers in Medicine
Streptococcal Infections and Treatments
article

Case Report: Streptococcus dysgalactiae ssp. dysgalactiae bloodstream infections in patients with breast cancer after radiotherapy and chemotherapy

Jingbai Chen, Zhixin You, Chongmei Tian, Yaping Zhao, Su Dong, Yong Fang, Hongfeng Xu
article en

Abstract

Bloodstream infections are life-threatening conditions in patients with breast cancer, especially among older individuals. Although the most common risk factor in these patients with tumors is the use of severe neutropenia secondary to myelosuppressive chemotherapy and radiotherapy, other factors are possibly associated with the invasive pathogenicity of microorganisms, including <i>Streptococcus dysgalactiae</i>. <i>Streptococcus dysgalactiae</i> ssp. <i>dysgalactiae (SDSD)</i> has been considered both an environmental pathogen and a contagious pathogen. However, there have been few reports of bloodstream infections with SDSD in patients with breast cancer after radiotherapy and chemotherapy. In this study, we report an interesting case of bloodstream infection caused by SDSD in an older patient with breast cancer after radiotherapy and chemotherapy. A 60-year-old Chinese woman had a history of breast cancer for 2 years. She developed chills and fever after puncturing blood blisters in the mouth, accompanied by fatigue and poor appetite. After 6 days of antimicrobial therapy, the patient showed gradual recovery. Bloodstream infections with SDSD in patients with breast cancer are rare. Therefore, accurate diagnosis and timely treatment can be lifesaving.

Frontiers in MedicineVol. 12
Zhejiang Chinese Medical University (CN)
Medical Science and Technology Project of Zhejiang Province
Openalex Percentile: Top 83%
Streptococcal Infections and Treatments
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