Design, Synthesis, Molecular Docking, and Biological Evaluation of 7-Phenyl-5-(thiophen-2-yl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-diones asAntibacterial Agents

All the compounds exhibited antibacterial activity against all the tested strains of bacteria with optimum ADME profile.

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Publication Details

Journal
Current Topics in Medicinal Chemistry
Published
2025-05-26
DOI
https://doi.org/10.2174/0115680266355090250407105802
Primary Topic
Synthesis and biological activity
Type
article
Field-Weighted Citation Impact
0.00
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article

Design, Synthesis, Molecular Docking, and Biological Evaluation of 7-Phenyl-5-(thiophen-2-yl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-diones asAntibacterial Agents

Harshwardhan Singh, Pradeep Kumar, Adarsh Kumar, Ankit Kumar Singh et al.
Current Topics in Medicinal Chemistry
Synthesis and biological activity
article

Design, Synthesis, Molecular Docking, and Biological Evaluation of 7-Phenyl-5-(thiophen-2-yl)pyrido[2,3-d]pyrimidine-2,4(1H,3H)-diones asAntibacterial Agents

Harshwardhan Singh, Pradeep Kumar, Adarsh Kumar, Ankit Kumar Singh, Balasubramanian Narasimhan, Mallika Agrawal
article en

Abstract

All the compounds exhibited antibacterial activity against all the tested strains of bacteria with optimum ADME profile.

Current Topics in Medicinal ChemistryVol. 25
Central University of Punjab (IN), Sam Higginbottom Institute of Agriculture (IN), Maharshi Dayanand University (IN)
Openalex Percentile: Top 91%
Synthesis and biological activity
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