Aldehyde Dehydrogenase 2 Gene Mutation May Reduce the Risk of Rupture of Intracranial Aneurysm in Chinese Han Population
The incidence of RIA was significantly higher in individuals with a normal ALDH2 gene (ALDH2*1/*1) than in those with an ALDH2 rs671 SNP (ALDH2*1/*2 or ALDH2*2/*2). ALDH2 rs671 SNP may serve as a protective factor against RIA in the Chinese Han population.
Authors
- Dingwei Deng
- Dachao Wei (ORCID: https://orcid.org/0000-0003-3389-8112)
- Wei You (ORCID: https://orcid.org/0000-0003-0071-6730)
- Siming Gui (ORCID: https://orcid.org/0000-0002-7024-7258)
- Huijian Ge
- Xiheng Chen (ORCID: https://orcid.org/0000-0002-7856-5461)
- Ming Lv (ORCID: https://orcid.org/0000-0003-1865-2309)
- Yudi Tang (ORCID: https://orcid.org/0000-0002-3436-7711)
- Yuhua Jiang (ORCID: https://orcid.org/0000-0001-7138-3748)
- Jia Jiang
- Peng Liu (ORCID: https://orcid.org/0000-0003-1198-4925)
- Yi Wang (ORCID: https://orcid.org/0000-0001-6965-9696)
- Lin Jun
- Youxiang Li (ORCID: https://orcid.org/0009-0004-8962-8079)
- Jian Lv (ORCID: https://orcid.org/0000-0002-5730-3614)
- Lixin Ma
Institutions
- Capital Medical University (CN)
- Beijing Institute of Neurosurgery (CN)
Publication Details
- Journal
- Journal of Stroke
- Published
- 2025-05-30
- DOI
- https://doi.org/10.5853/jos.2024.04098
- Citations
- 1
- Primary Topic
- Intracranial Aneurysms: Treatment and Complications
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Natural Science Foundation of China