Comparison of safety of lecanemab and aducanumab: a real-world disproportionality analysis using the FDA adverse event reporting system

Four signal calculation methods were used to assess potential adverse reaction signals of lecanemab and aducanumab. This study identified some new PT signals and some PT signals showed gender differences. The median time-to-onset of ADEs due to lecanemab is shorter than that due to aducanumab.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2025-05-30
DOI
https://doi.org/10.3389/fphar.2025.1593989
Citations
4
Primary Topic
Health Systems, Economic Evaluations, Quality of Life
Type
article
Field-Weighted Citation Impact
12.52
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article

Comparison of safety of lecanemab and aducanumab: a real-world disproportionality analysis using the FDA adverse event reporting system

Lingti Kong, Xiaohu Yang, Jianming Xu
4 citations
Frontiers in Pharmacology
Health Systems, Economic Evaluations, Quality of Life
12.52
article

Comparison of safety of lecanemab and aducanumab: a real-world disproportionality analysis using the FDA adverse event reporting system

Lingti Kong, Xiaohu Yang, Jianming Xu
article en
4 citations

Abstract

Four signal calculation methods were used to assess potential adverse reaction signals of lecanemab and aducanumab. This study identified some new PT signals and some PT signals showed gender differences. The median time-to-onset of ADEs due to lecanemab is shorter than that due to aducanumab.

Frontiers in PharmacologyVol. 16
Bengbu Medical College (CN), First Affiliated Hospital of Bengbu Medical College (CN)
Openalex Percentile: Top 2%
Health Systems, Economic Evaluations, Quality of Life
12.52
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