IgA autoimmunity and coagulation among post-acute sequelae of SARS-CoV-2 infection (PASC) patients with persistent respiratory symptoms: a case-control study
Our small study of PASC patients identified that circulating IgA antibodies may correlate inversely with clinical symptoms and directly with clotting parameters, suggesting a possible link between autoimmunity and coagulation. However, many of the study's findings were null, which may mean that tissue-level studies or alternative explanations of PASC need to be explored.
Authors
- Ana Rodrı́guez (ORCID: https://orcid.org/0000-0002-0060-3405)
- Jonathan Whiteson
- Marisol Zuniga
- Cláudia Gomes (ORCID: https://orcid.org/0000-0003-3746-1671)
- Rany Condos
- Mila Brum Ortigoza (ORCID: https://orcid.org/0000-0002-9428-1469)
- David C. Lee
- Fabio Ponzo
Institutions
- New York University (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-30
- DOI
- https://doi.org/10.3389/fimmu.2025.1589559
- Primary Topic
- Long-Term Effects of COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- NYU Langone Medical Center
- Georgia Clinical and Translational Science Alliance
- National Institutes of Health
- School of Medicine, New York University
- National Center for Advancing Translational Sciences