A non-invasive method for screening mitochondrial diabetes
The detection of the m.3243A>G mutation through the collection of oral exfoliated cells offers several advantages over other methods, including simplicity, non-invasiveness, and high specificity and sensitivity. However, it is currently underutilized. Therefore, further experiments are needed to study and validate this approach in order to optimize MDM screening methods and improve diagnostic rates for MDM.
Authors
- Hua Fang (ORCID: https://orcid.org/0000-0003-1669-4898)
- Xiaoe Li
- Chao Xu (ORCID: https://orcid.org/0000-0002-6398-4129)
- Victor Wei Zhang (ORCID: https://orcid.org/0000-0002-7335-1472)
- Shuping Wang (ORCID: https://orcid.org/0000-0002-8702-8780)
- Mei Zhang (ORCID: https://orcid.org/0000-0003-0976-3867)
Institutions
- Ministry of Education of the People's Republic of China (CN)
- Wenzhou Medical University (CN)
- Shandong Provincial Hospital (CN)
- ID Genomics (United States) (US)
- Dongyang People's Hospital (CN)
- Affiliated Hospital of Jining Medical University (CN)
- Jingning County People's Hospital (CN)
- Shandong First Medical University (CN)
- Shandong Academy of Chinese Medicine (CN)
- Shandong Center for Disease Control and Prevention (CN)
Publication Details
- Journal
- Frontiers in Genetics
- Published
- 2025-05-30
- DOI
- https://doi.org/10.3389/fgene.2025.1536331
- Citations
- 1
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 1.16
Funders
- National Key Research and Development Program of China