Fusarium spp. and Aspergillus flavus infection induces pathogen-specific and pathogen-independent host immune response in patients with fungal keratitis
RT-qPCR confirmed the key pathogen-specific DEGs, highlighting their potential as biomarkers for pathogen-specific immune responses. These findings provide insights into the distinct immune pathways triggered by <i>Fusarium</i> spp. and <i>A. flavus</i>, offering new therapeutic targets for improving fungal keratitis treatment.
Authors
- Bharanidharan Devarajan (ORCID: https://orcid.org/0000-0002-2193-4609)
- Kuppamuthu Dharmalingam
- Prajna Namperumalsamy Venkatesh
- Prajna Lalitha (ORCID: https://orcid.org/0000-0001-5379-7015)
- S. Dinesh (ORCID: https://orcid.org/0000-0002-9663-0650)
Institutions
- Madurai Kamaraj University (IN)
- Aravind Eye Hospital (IN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-05-30
- DOI
- https://doi.org/10.3389/fcimb.2025.1560628
- Citations
- 1
- Primary Topic
- Ocular Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.71
Funders
- Indian Council of Medical Research