Effect of exercise training on cardiac function and glucose metabolism in the ischemic border zone: insights from multi-modal imaging techniques
Early exercise post-AMI, as assessed by CMR and PET imaging, significantly improved cardiac function, reduced myocardial remodeling, and enhanced glucose metabolism. These benefits were mediated through the upregulation of GLUT4 and PFKFB3 expression, underscoring the potential of exercise as a therapeutic strategy in post-AMI management.
Authors
- Yuxin Xiao (ORCID: https://orcid.org/0000-0001-7251-6557)
- Tianshuo Zhang (ORCID: https://orcid.org/0000-0002-7920-4473)
- Jianbo Cao (ORCID: https://orcid.org/0000-0002-0859-1680)
- C Jin
- Min Zhang (ORCID: https://orcid.org/0000-0003-0384-2038)
- Jun Zhang (ORCID: https://orcid.org/0000-0002-8760-6747)
- Ruonan Wang (ORCID: https://orcid.org/0000-0002-7574-1810)
- Xiao Han (ORCID: https://orcid.org/0000-0003-3869-2367)
- Zhifang Wu
- Sheng He (ORCID: https://orcid.org/0000-0003-2918-1549)
- Ping Wu (ORCID: https://orcid.org/0000-0002-0788-6268)
- Sijin Li (ORCID: https://orcid.org/0000-0003-0361-1248)
- Hongju Guo
- Li Li (ORCID: https://orcid.org/0000-0001-9982-0460)
Institutions
- Shanxi Medical University (CN)
- First Hospital of Shanxi Medical University (CN)
Publication Details
- Journal
- Frontiers in Cardiovascular Medicine
- Published
- 2025-05-30
- DOI
- https://doi.org/10.3389/fcvm.2025.1583206
- Primary Topic
- Cardiac Imaging and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China