Diagnostic value of methane-hydrogen breath test combined with intestinal flora testing in screening for colorectal polyps
HBT provides a non-invasive strategy for colorectal polyp screening by capturing CH<sub>4</sub>/H<sub>2</sub> metabolic gases with intestinal flora characteristics. Combining flora markers significantly improves diagnostic efficacy, suggesting its translational potential in optimizing screening pathways. Future exploration of the mechanisms of flora-metabolic gas dynamic interactions and individualized threshold setting is warranted.
Authors
- Wei Qiang Wang (ORCID: https://orcid.org/0000-0002-1430-1360)
- Xiaohui Wang (ORCID: https://orcid.org/0000-0002-5053-1008)
- Hui Li (ORCID: https://orcid.org/0000-0002-5604-0592)
- Rui Li (ORCID: https://orcid.org/0000-0001-5448-6868)
- Zhihui Yan (ORCID: https://orcid.org/0000-0002-8993-3426)
- Lihong Cui (ORCID: https://orcid.org/0000-0003-3007-728X)
- Yan Zheng
Institutions
- Chinese PLA General Hospital (CN)
- PLA Academy of Military Science (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-05-30
- DOI
- https://doi.org/10.3389/fmed.2025.1530558
- Primary Topic
- Colorectal Cancer Screening and Detection
- Type
- article
- Field-Weighted Citation Impact
- 0.00