Rare case report: Liver metastasis from cervical adenocarcinoma presenting with cystic mass and obstructive jaundice

Liver metastases can originate from primary tumors in various organs; however, metastasis from cervical cancer to the liver is rare. Cervical cancer patients with distant metastases have a poor prognosis and reduced survival rates. This report describes a case of a cystic liver mass with obstructive jaundice, observed four years after resection of cervical adenocarcinoma. The lesion lacked typical imaging characteristics of hepatic metastases and was initially suspected to be a biliary neoplasm. A contrast-enhanced, ultrasound-guided needle biopsy was performed to confirm the diagnosis. Histopathological analysis confirmed adenocarcinoma of the liver, and immunohistochemical staining suggested a uterine or adnexal origin. Considering the patient's surgical history, the final diagnosis was liver metastasis originating from cervical adenocarcinoma. This report reviews relevant literature to discuss the clinical features, diagnostic challenges, and therapeutic strategies for liver metastasis of cervical cancer.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-05-30
DOI
https://doi.org/10.3389/fonc.2025.1558946
Primary Topic
Cancer Diagnosis and Treatment
Type
article
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article

Rare case report: Liver metastasis from cervical adenocarcinoma presenting with cystic mass and obstructive jaundice

Jin Li, Le Luo, Xin Wei
Frontiers in Oncology
Cancer Diagnosis and Treatment
article

Rare case report: Liver metastasis from cervical adenocarcinoma presenting with cystic mass and obstructive jaundice

Jin Li, Le Luo, Xin Wei
article en

Abstract

Liver metastases can originate from primary tumors in various organs; however, metastasis from cervical cancer to the liver is rare. Cervical cancer patients with distant metastases have a poor prognosis and reduced survival rates. This report describes a case of a cystic liver mass with obstructive jaundice, observed four years after resection of cervical adenocarcinoma. The lesion lacked typical imaging characteristics of hepatic metastases and was initially suspected to be a biliary neoplasm. A contrast-enhanced, ultrasound-guided needle biopsy was performed to confirm the diagnosis. Histopathological analysis confirmed adenocarcinoma of the liver, and immunohistochemical staining suggested a uterine or adnexal origin. Considering the patient's surgical history, the final diagnosis was liver metastasis originating from cervical adenocarcinoma. This report reviews relevant literature to discuss the clinical features, diagnostic challenges, and therapeutic strategies for liver metastasis of cervical cancer.

Frontiers in OncologyVol. 15
Deyang Stomatological Hospital (CN)
Openalex Percentile: Top 81%
Cancer Diagnosis and Treatment
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Rare case report: Liver metastasis from cervical adenocarcinoma presenting with cystic mass and obstructive jaundice — Jin Li, Le Luo, et al. · Frontiers in Oncology (2025) | TGRS Research Map | TGRS