Potential cerebrospinal fluid metabolomic biomarkers and early prediction model for Parkinson’s disease
The differential expression of CSF metabolites reveals early cellular metabolic changes, providing insights for early diagnosis and monitoring PD progression. A bidirectional causal relationship exists between genetically determined PD susceptibility and metabolites.
Authors
- Shengyuan Su (ORCID: https://orcid.org/0009-0003-3146-6719)
- Xiangxu Kong
- Yifan Zhang (ORCID: https://orcid.org/0000-0001-7650-1109)
- Yuexin Yan
- Haijun Zhang (ORCID: https://orcid.org/0000-0002-9198-8098)
Institutions
- Shenzhen Bao'an District People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2025-05-30
- DOI
- https://doi.org/10.3389/fnagi.2025.1582362
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Bristol-Myers Squibb
- Eli Lilly and Company
- Pfizer
- Sanofi
- Biogen
- Teva Pharmaceutical Industries
- Celgene
- Jazz Pharmaceuticals
- Neurocrine Biosciences
- Verily Life Sciences
- Voyager Therapeutics
- Servier
- H. Lundbeck A/S
- Sun Pharma
- Genentech
- Allergan
- Avid Radiopharmaceuticals