Males and females respond differently to treatment during isolated kidney perfusion: combined effects of glucocorticoid and estradiol

The combined treatment of E2 and MP during isolated kidney perfusion compromised kidney function in females. In males, no detrimental effects were observed. These results show a sex-dependent action of the proposed treatment.

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Publication Details

Journal
Frontiers in Transplantation
Published
2025-05-30
DOI
https://doi.org/10.3389/frtra.2025.1595766
Primary Topic
Renal Transplantation Outcomes and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

Males and females respond differently to treatment during isolated kidney perfusion: combined effects of glucocorticoid and estradiol

Henri G. D. Leuvenink, Cristiano de Jesus Correia, Ana Cristina Breithaupt‐Faloppa, Lucas Ferreira da Anunciação et al.
Frontiers in Transplantation
Renal Transplantation Outcomes and Treatments
article

Males and females respond differently to treatment during isolated kidney perfusion: combined effects of glucocorticoid and estradiol

Henri G. D. Leuvenink, Cristiano de Jesus Correia, Ana Cristina Breithaupt‐Faloppa, Lucas Ferreira da Anunciação, Petra J. Ottens, Roberto Armstrong, Marina Vidal‐dos‐Santos, Mayara Munhóz de Assis Ramos, Luíz Felipe Pinho Moreira, Fernanda Yamamoto Ricardo‐da‐Silva
article en

Abstract

The combined treatment of E2 and MP during isolated kidney perfusion compromised kidney function in females. In males, no detrimental effects were observed. These results show a sex-dependent action of the proposed treatment.

Frontiers in TransplantationVol. 4
University Medical Center Groningen (NL), University of Groningen (NL), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (BR)
Rijksuniversiteit Groningen, Fundação de Amparo à Pesquisa do Estado de São Paulo, Conselho Nacional de Desenvolvimento Científico e Tecnológico
Openalex Percentile: Top 85%
Renal Transplantation Outcomes and Treatments
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