YTHDF2-mediated m6A modification regulates mRNA stability of Immediate early response gene 3 to modulate cell death in Staphylococcus aureus-induced bovine mastitis
YTHDF2 regulates m<sup>6</sup>A-modified mRNA stability to modulate apoptosis and inflammation during <i>S. aureus</i> infection. These findings provide new insights into understanding the molecular mechanisms of bovine mastitis and provide genetic markers for breeding mastitis-resistant dairy cows.
Authors
- Ying Yu (ORCID: https://orcid.org/0000-0002-4524-0791)
- Siyuan Mi (ORCID: https://orcid.org/0000-0003-4950-689X)
- Yue Xing (ORCID: https://orcid.org/0000-0001-5845-2286)
- Yuanjun Shi
- Xingping Wang (ORCID: https://orcid.org/0000-0002-5219-2230)
- Xinyue Tao
- Zihan Zhang
- Siqian Chen (ORCID: https://orcid.org/0009-0004-4737-7443)
Institutions
- Ningxia University (CN)
- Westlake University (CN)
- Ministry of Agriculture (ID)
- Ministry of Agriculture and Rural Affairs (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-05-30
- DOI
- https://doi.org/10.3389/fcimb.2025.1542647
- Citations
- 2
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China
- China Agricultural University
- Natural Science Foundation for Young Scientists of Shanxi Province
- Young Scientists Fund
- National Key Research and Development Program of China