The associations among serum vitamin D concentration, systemic immune-inflammation index, and lifestyle factors in Chinese adults: a cross-sectional analysis

These results substantiate the association between vitamin D levels and the SII while suggesting that interventions targeting lifestyle modifications may positively impact vitamin D status, thereby ameliorating systemic chronic inflammation. Although this study provides preliminary evidence regarding the interplay between vitamin D deficiency and systemic inflammatory processes, further investigations are warranted to elucidate the underlying biological mechanisms and explore potential strategies for regulating vitamin D concentrations through improved lifestyles and dietary choices.