Transcriptomic analysis of mammary gland tissues in lactating and non-lactating dairy goats reveals miRNA-mediated regulation of lactation, involution, and remodeling
This study highlights the dynamic regulatory roles of miRNAs in the goat mammary gland across lactation stages. Notably, the miR-423-3p/IGF1R axis is a key regulator of mammary remodeling during the dry period, offering new insights into the molecular basis of mammary gland functional transitions.
Authors
- Xinhua Duan
- Weiping Ao
- Yue Guo (ORCID: https://orcid.org/0000-0003-4881-9923)
- Yanan Peng
- Rong Xuan (ORCID: https://orcid.org/0000-0001-5548-432X)
- Linfan Zhang
- Jinglin Cao (ORCID: https://orcid.org/0009-0004-4703-7246)
Institutions
- Tarim University (CN)
- Animal Husbandry & Veterinary (IN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-05-30
- DOI
- https://doi.org/10.3389/fcell.2025.1604855
- Citations
- 1
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.94