Microbiological colonization of the pancreatic tumor affects postoperative complications and outcome after pancreatic surgery
In this first analysis of our patient cohort, we could show a microbiological colonization of pancreatic tumor tissue in almost a third of our patients. There seems to be only a minor impact on postoperative complications, but long-term outcome seems to be worse in patients with a positive pancreas microbiome. Further observation is needed to evaluate the influence of the tumor microbiome on the long-term oncological outcome in PDAC patients.
Authors
- Sara Posadas‐Cantera (ORCID: https://orcid.org/0000-0003-3607-8929)
- Esther A. Biesel (ORCID: https://orcid.org/0000-0003-4597-0943)
- Uwe A. Wittel (ORCID: https://orcid.org/0000-0001-6194-2374)
- Mohamed Tarek Badr (ORCID: https://orcid.org/0000-0002-8800-6380)
- Sophia Chikhladze (ORCID: https://orcid.org/0000-0001-6235-147X)
- Stefan Fichtner‐Feigl (ORCID: https://orcid.org/0000-0002-6710-562X)
- Johanna Sundheimer
Institutions
- University of Freiburg (DE)
- University Medical Center Freiburg (DE)
- Institute of Medical Microbiology and Hygiene (DE)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-05-30
- DOI
- https://doi.org/10.3389/fcimb.2025.1521952
- Citations
- 2
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 2.09