Analyze the effects of A paniculata leaf extract in methanol on Candida albicans RFG1 gene expression

The gene expression studies showed decreased level of Rfg1 gene expression in C. albicans upon treatment with methanolic leaf extracts of A. paniculata. However, similar molecular studies on pure compounds from this plant may give strong evidences about the pharmacological potential of the plant and thus can be formulated as an effective drug for the treatment of infections caused by C. albicans. The bioassays on antifungal activity of the methanolic leaf extract of A. paniculata showed inhibitory effects against human pathogen C. albicans.

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Publication Details

Journal
International Journal of Molecular Biology Open Access
Published
2025-01-01
DOI
https://doi.org/10.15406/ijmboa.2025.08.00194
Primary Topic
Antifungal resistance and susceptibility
Type
article
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article

Analyze the effects of A paniculata leaf extract in methanol on Candida albicans RFG1 gene expression

Muniyandi Nagarajan, P Sagadevan, Aruna Devi, Vijith Kumar et al.
International Journal of Molecular Biology Open Access
Antifungal resistance and susceptibility
article

Analyze the effects of A paniculata leaf extract in methanol on Candida albicans RFG1 gene expression

Muniyandi Nagarajan, P Sagadevan, Aruna Devi, Vijith Kumar, Michael Raghunath, Charles J. Paul, N Sribala, P Kavipriya
article en

Abstract

The gene expression studies showed decreased level of Rfg1 gene expression in C. albicans upon treatment with methanolic leaf extracts of A. paniculata. However, similar molecular studies on pure compounds from this plant may give strong evidences about the pharmacological potential of the plant and thus can be formulated as an effective drug for the treatment of infections caused by C. albicans. The bioassays on antifungal activity of the methanolic leaf extract of A. paniculata showed inhibitory effects against human pathogen C. albicans.

International Journal of Molecular Biology Open AccessVol. 8(1)
Openalex Percentile: Top 84%
Antifungal resistance and susceptibility
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Analyze the effects of A paniculata leaf extract in methanol on Candida albicans RFG1 gene expression — Muniyandi Nagarajan, P Sagadevan, et al. · International Journal of Molecular Biology Open Access (2025) | TGRS Research Map | TGRS