Prenatal modulation of NADPH-oxidase reverses the deranged GABA switch and rescues behavioral deficits in valproate ASD rat model
These results suggest that targeting the NOX-ROS pathway may be a potential therapeutic strategy for ASD.
Authors
- Soha Elmorsy (ORCID: https://orcid.org/0000-0003-2947-9353)
- Aya A. Elkhodiry (ORCID: https://orcid.org/0000-0001-5684-0242)
- Aya Samir (ORCID: https://orcid.org/0000-0002-1592-9125)
- Azza G. Kamel
- Engy A. Abdel‐Rahman
- Ebtehal El‐Demerdash (ORCID: https://orcid.org/0000-0003-2951-4892)
- Christine Prince (ORCID: https://orcid.org/0000-0002-3237-5953)
- Basma A. Yasseen (ORCID: https://orcid.org/0000-0003-4187-0523)
- Rehab M. Hamdy (ORCID: https://orcid.org/0000-0002-8188-6792)
- Sameh S. Ali (ORCID: https://orcid.org/0000-0002-0339-6106)
- Nouran Al‐Shehaby (ORCID: https://orcid.org/0000-0002-2559-0428)
- Ghada Z A Soliman (ORCID: https://orcid.org/0000-0003-4070-3854)
- Hajar El-sayed
- Malak W. Elbenhawi
- Tamer M. Gamal El-Din (ORCID: https://orcid.org/0000-0002-7406-7393)
- Aya Galal (ORCID: https://orcid.org/0000-0002-1474-759X)
- Yasmin Hatem
- Mohamed A. Badawy
- Hadeer Abdelkhalek
- Sara Gohar
Institutions
- Ain Shams University (EG)
- Cairo University (EG)
- University of Washington (US)
- Cancer Research UK (GB)
- Children Cancer Hospital (EG)
- Assiut University (EG)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-05-30
- DOI
- https://doi.org/10.3389/fphar.2025.1571008
- Citations
- 1
- Primary Topic
- Pharmacological Effects and Toxicity Studies
- Type
- article
- Field-Weighted Citation Impact
- 3.49
Funders
- Science and Technology Development Fund