Cognitive development at late infancy and school age in children cooled for neonatal encephalopathy
Bayley-III underestimates school-age delays in children cooled for neonatal encephalopathy secondary to perinatal asphyxia (NE). Around 45% of children's cognitive scores moved to a lower developmental range at school age. Increasing the Bayley-III threshold to 95 failed to identify nearly two-thirds of children with IQ < 85. Childhood IQ after NE appeared to be patterned by local deprivation. Longitudinal monitoring of children cooled for neonatal encephalopathy secondary to perinatal asphyxia is needed to support their cognitive development.
Authors
- Sally Jary (ORCID: https://orcid.org/0000-0003-1335-1726)
- David Odd (ORCID: https://orcid.org/0000-0002-6416-4966)
- Ross E. Vanderwert (ORCID: https://orcid.org/0000-0002-2280-8401)
- Ela Chakkarapani (ORCID: https://orcid.org/0000-0003-3380-047X)
- Sara Rapuc
Institutions
- University Hospitals Bristol NHS Foundation Trust (GB)
- University of Bristol (GB)
- Cardiff University (GB)
Publication Details
- Journal
- Pediatric Research
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1038/s41390-025-04152-4
- Citations
- 2
- Primary Topic
- Neonatal and fetal brain pathology
- Type
- article
- Field-Weighted Citation Impact
- 6.99
Funders
- UK Research and Innovation
- Medical Research Council