The brain shock index: repurposing the Lindegaard ratio for detecting cerebral hypoperfusion in children with cerebral malaria

The BSI is a rapid, feasible point of care ultrasound measurement of cerebral hypoperfusion, with values ≤ 1.1 strongly correlating with poor neurologic outcomes in children with CM. Future studies should be performed to assess the utility of BSI to detect the presence and measure the severity of reduced cerebral perfusion pressure in other populations of critically ill children.

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Publication Details

Journal
The Ultrasound Journal
Published
2025-05-30
DOI
https://doi.org/10.1186/s13089-025-00430-8
Primary Topic
Traumatic Brain Injury and Neurovascular Disturbances
Type
article
Field-Weighted Citation Impact
0.00

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article

The brain shock index: repurposing the Lindegaard ratio for detecting cerebral hypoperfusion in children with cerebral malaria

Jean Pongo Mbaka, Taty Tshimanga, Montfort Bernard Gushu, Nicole O’Brien et al.
The Ultrasound Journal
Traumatic Brain Injury and Neurovascular Disturbances
article

The brain shock index: repurposing the Lindegaard ratio for detecting cerebral hypoperfusion in children with cerebral malaria

Jean Pongo Mbaka, Taty Tshimanga, Montfort Bernard Gushu, Nicole O’Brien, Robert Tandjeka Ekandji, Ludovic Mayindombe, Tusekile Phiri, Sylvester June, Marlina E. Lovett, Hunter Wynkoop, Florette Yumsa Mangwangu
article en

Abstract

The BSI is a rapid, feasible point of care ultrasound measurement of cerebral hypoperfusion, with values ≤ 1.1 strongly correlating with poor neurologic outcomes in children with CM. Future studies should be performed to assess the utility of BSI to detect the presence and measure the severity of reduced cerebral perfusion pressure in other populations of critically ill children.

The Ultrasound JournalVol. 17(1)
Nationwide Children's Hospital (US), Kinshasa General Hospital (CD), University of Łódź (PL), University of Kinshasa (CD), Queen Elizabeth Central Hospital (MW), The Ohio State University (US)
National Institute of Child Health and Human Development
Good health and well-being
Openalex Percentile: Top 80%
Traumatic Brain Injury and Neurovascular Disturbances
DOIOpen Access PDFOpenAlex
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The brain shock index: repurposing the Lindegaard ratio for detecting cerebral hypoperfusion in children with cerebral malaria — Jean Pongo Mbaka, Taty Tshimanga, et al. · The Ultrasound Journal (2025) | TGRS Research Map | TGRS