Development and Optimization of Oral Dissolution Films for Enhanced Delivery of Ebastine-Loaded Solid Lipid Nanoparticles

The developed system demonstrates enhanced solubility, stability, and bioavailability of ebastine, offering a promising alternative to traditional oral tablets, with potential advantages in patient compliance and rapid drug onset. Therefore, the ODFs containing SLNs can be considered as an efficient approach for EBT administration.

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Publication Details

Journal
International Journal of Nanomedicine
Published
2025-05-01
DOI
https://doi.org/10.2147/ijn.s521504
Citations
2
Primary Topic
Advancements in Transdermal Drug Delivery
Type
article
Field-Weighted Citation Impact
1.58
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article

Development and Optimization of Oral Dissolution Films for Enhanced Delivery of Ebastine-Loaded Solid Lipid Nanoparticles

Kai Chen, Yong Sun
2 citations
International Journal of Nanomedicine
Advancements in Transdermal Drug Delivery
1.58
article

Development and Optimization of Oral Dissolution Films for Enhanced Delivery of Ebastine-Loaded Solid Lipid Nanoparticles

Kai Chen, Yong Sun
article en
2 citations

Abstract

The developed system demonstrates enhanced solubility, stability, and bioavailability of ebastine, offering a promising alternative to traditional oral tablets, with potential advantages in patient compliance and rapid drug onset. Therefore, the ODFs containing SLNs can be considered as an efficient approach for EBT administration.

International Journal of NanomedicineVol. Volume 20
Qingdao University (CN), Affiliated Hospital of Jining Medical University (CN)
Openalex Percentile: Top 17%
Advancements in Transdermal Drug Delivery
1.58
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