Research Advances in TCM Syndromes of Postmenopausal Osteoporosis Based on Metabolomics

代谢组学作为系统生物学的重要分支，为中医证候研究提供了新的技术手段。本文首先介绍了绝经后骨质疏松症的中医证候分类、特点及相关研究，随后阐述了代谢组学在绝经后骨质疏松症的应用现状。重点分析了代谢组学在绝经后骨质疏松症中医证候研究中的具体应用，包括不同证候的代谢特征、生物标志物筛选及证候本质阐释等方面。As a crucial branch of systems biology, metabolomics provides a novel technical approach for studying Traditional Chinese Medicine (TCM) syndromes. This article first introduces the classification, characteristics, and related research on TCM syndromes of postmenopausal osteoporosis (PMO). Subsequently, it summarizes the current applications of metabolomics in PMO research. The focus lies in analyzing the specific roles of metabolomics in TCM syndrome studies of PMO, including the identification of metabolic characteristics across different syndromes, screening of biomarkers, and elucidation of syndrome essences. By integrating metabolomic data with TCM theory, this approach offers a holistic perspective for understanding the pathogenesis of PMO and advancing personalized TCM interventions.