Serum immunoreactivity to neurofilament-medium shows high sensitivity and specificity in patients with Behçet disease
These findings reveal the ubiquitous presence of NF-M immunoreactivity, reportedly cross-reacting with bacterial heat shock protein 65, in BD sera. This common and specific immunoreactivity may serve as a valuable tool for diagnosing BD. Additionally, the data confirm the unique potential of connective tissue-poor brain sections for identifying sero-immunoreactivity.
Authors
- Aslı Tuncer (ORCID: https://orcid.org/0000-0001-9449-4483)
- Sibel Kadayıfçılar (ORCID: https://orcid.org/0000-0002-5238-9535)
- Turgay Dalkara (ORCID: https://orcid.org/0000-0003-3943-7819)
- Şefik Evren Erdener (ORCID: https://orcid.org/0000-0002-5141-7899)
- Gizem Ayan (ORCID: https://orcid.org/0000-0003-1889-9619)
- Tayfun Hilmi Akbaba (ORCID: https://orcid.org/0000-0002-3875-5244)
- Ayşe İlksen Çolpak (ORCID: https://orcid.org/0000-0002-2138-7051)
- Yeliz Z. Akkaya‐Ulum (ORCID: https://orcid.org/0000-0003-1888-2542)
- Banu Balcı‐Peynircioğlu (ORCID: https://orcid.org/0000-0002-8627-8796)
- Buket Dönmez‐Demir
- Umut Kalyoncu (ORCID: https://orcid.org/0000-0001-7129-2109)
Institutions
- Bilkent University (TR)
- Hacettepe University (TR)
Publication Details
- Journal
- RMD Open
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1136/rmdopen-2024-005100
- Primary Topic
- Ocular Diseases and Behçet’s Syndrome
- Type
- article
- Field-Weighted Citation Impact
- 0.00