Extranasopharyngeal Angiofibroma of Maxillary Sinus: A Diagnostic Dilemma

Nasopharyngeal angiofibroma is a benign neoplasm of the nasopharynx with a propensity for aggressive local spread. It is responsible for 0.5% of head and neck cancer cases. Primarily affected are teenagers and young adults in the agerange of 14–25 years. It is an aggressive tumor that frequently spreads locally, destructive, including the base of the skull and the cranium. Evidence points to an androgen-dependent tumor given the substantial preference for young guys. Usually, the tumor originates around the sphenopalatine foramen. We present a case of angiofibroma in a young adult arising from the lateral wall of the nasal cavity around the maxillary sinus, masquerading as an antrochoanal polyp. Diagnostic nasal endoscopy was suggestive of an antrochoanal polyp. NCCT nose and PNS showed that the tumor originated from the lateral wall of the nasal cavity around maxillary sinus ostium with and left maxillary sinus opacification. Histopathological examination shows dense fibrocollagenous stromal proliferation interspersed with staghorns of various sizes and numerous thin-walled vessels, characteristic features of juvenile nasopharyngeal angiofibroma. After surgical resection, the person was followed for up to six months without tumor recurrence.

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Publication Details

Journal
International Journal of Contemporary Pathology
Published
2025-05-30
DOI
https://doi.org/10.37506/tawkkj25
Primary Topic
Head and Neck Surgical Oncology
Type
article
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article

Extranasopharyngeal Angiofibroma of Maxillary Sinus: A Diagnostic Dilemma

Dayal Singh Bisht, Sunita Bisht
International Journal of Contemporary Pathology
Head and Neck Surgical Oncology
article

Extranasopharyngeal Angiofibroma of Maxillary Sinus: A Diagnostic Dilemma

Dayal Singh Bisht, Sunita Bisht
article en

Abstract

Nasopharyngeal angiofibroma is a benign neoplasm of the nasopharynx with a propensity for aggressive local spread. It is responsible for 0.5% of head and neck cancer cases. Primarily affected are teenagers and young adults in the agerange of 14–25 years. It is an aggressive tumor that frequently spreads locally, destructive, including the base of the skull and the cranium. Evidence points to an androgen-dependent tumor given the substantial preference for young guys. Usually, the tumor originates around the sphenopalatine foramen. We present a case of angiofibroma in a young adult arising from the lateral wall of the nasal cavity around the maxillary sinus, masquerading as an antrochoanal polyp. Diagnostic nasal endoscopy was suggestive of an antrochoanal polyp. NCCT nose and PNS showed that the tumor originated from the lateral wall of the nasal cavity around maxillary sinus ostium with and left maxillary sinus opacification. Histopathological examination shows dense fibrocollagenous stromal proliferation interspersed with staghorns of various sizes and numerous thin-walled vessels, characteristic features of juvenile nasopharyngeal angiofibroma. After surgical resection, the person was followed for up to six months without tumor recurrence.

International Journal of Contemporary PathologyVol. 11(1)
Military Hospital (PK), Institute of Medical Sciences (IN)
Openalex Percentile: Top 79%
Head and Neck Surgical Oncology
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Extranasopharyngeal Angiofibroma of Maxillary Sinus: A Diagnostic Dilemma — Dayal Singh Bisht, Sunita Bisht · International Journal of Contemporary Pathology (2025) | TGRS Research Map | TGRS