Quality of life after risk reducing mastectomy in a Portuguese cohort of BRCA pathogenic/likely pathogenic variant carriers
No significant differences were found in psychologic distress levels between the IBS and RRM group. Although RRM is an effective method for reducing breast cancer risk in women with P/LP variants in BRCA1/2 genes, carriers should be informed of its impact on quality of life. Notably, once a woman is diagnosed with breast cancer, these differences lose effect.
Authors
- Sara Torres (ORCID: https://orcid.org/0000-0002-3710-2823)
- Raquel Meirelles Gaspar Coelho Guimarães (ORCID: https://orcid.org/0000-0002-6687-2018)
- Luzia Garrido (ORCID: https://orcid.org/0000-0001-5877-2917)
- Bárbara Peleteiro (ORCID: https://orcid.org/0000-0002-0579-9988)
- José Luís Fougo (ORCID: https://orcid.org/0000-0003-1861-8178)
- André Magalhães (ORCID: https://orcid.org/0000-0001-6249-7962)
- Susy Costa
- M Raposo
- Inês Insua-Pereira
Institutions
- Universidade do Porto (PT)
- Hospital de São João (PT)
- Administração Regional de Saúde de Lisboa e Vale do Tejo (PT)
- i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto (PT)
Publication Details
- Journal
- Journal of Cancer Research and Clinical Oncology
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1007/s00432-025-06231-9
- Citations
- 1
- Primary Topic
- BRCA gene mutations in cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- Universidade do Porto
- Third Health Programme