Synthesis of α-trifluoromethoxy-sulfide through the Pummerer rearrangement
A novel synthetic protocol for α-trifluoromethoxy sulfides was developed, characterized by mild reaction conditions and excellent substrate compatibility, which could be successfully employed for late-stage fluorination of pharmaceutically active molecules.
Authors
- Pingping Tang (ORCID: https://orcid.org/0000-0002-8296-5695)
- Z. Hong Zhou (ORCID: https://orcid.org/0000-0002-8373-4717)
- Mingrui Zhao (ORCID: https://orcid.org/0009-0006-3882-8526)
Institutions
- Nankai University (CN)
Publication Details
- Journal
- Organic & Biomolecular Chemistry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5ob00673b
- Citations
- 1
- Primary Topic
- Fluorine in Organic Chemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.79
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Tianjin City
- National Key Research and Development Program of China
- Fundamental Research Funds for the Central Universities