Dual bilateral stimulation of the nucleus accumbens and the centromedian thalamus for treatment of intractable Tourette syndrome

Following DBS placement, the patient experienced substantial improvement from his preoperative violent behavior and mood lability. This case provides evidence that dual electrode DBS, in conjunction with appropriate medical management, is a safe and effective way to improve life quality in individuals struggling with debilitating TS symptoms.

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Publication Details

Journal
Surgical Neurology International
Published
2025-05-30
DOI
https://doi.org/10.25259/sni_379_2025
Primary Topic
Obsessive-Compulsive Spectrum Disorders
Type
article
Field-Weighted Citation Impact
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article

Dual bilateral stimulation of the nucleus accumbens and the centromedian thalamus for treatment of intractable Tourette syndrome

Anand V. Germanwala, Chloe Verducci, Diego D. Luy, J Simon et al.
Surgical Neurology International
Obsessive-Compulsive Spectrum Disorders
article

Dual bilateral stimulation of the nucleus accumbens and the centromedian thalamus for treatment of intractable Tourette syndrome

Anand V. Germanwala, Chloe Verducci, Diego D. Luy, J Simon, Dayna C. Sloane, Arba Cecia, Nathan C. Pecoraro, Daryn K. Cass, Oleksandr Strelko, Marco Angelo, Jordan C. Iordanou, Douglas E. Anderson, Andrew S. Ghannad
article en

Abstract

Following DBS placement, the patient experienced substantial improvement from his preoperative violent behavior and mood lability. This case provides evidence that dual electrode DBS, in conjunction with appropriate medical management, is a safe and effective way to improve life quality in individuals struggling with debilitating TS symptoms.

Surgical Neurology InternationalVol. 16
Loyola University Medical Center (US), University of Massachusetts Chan Medical School (US), Loyola University Chicago (US), Community Hospital (US), The University of Texas Southwestern Medical Center (US)
Openalex Percentile: Top 83%
Obsessive-Compulsive Spectrum Disorders
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Dual bilateral stimulation of the nucleus accumbens and the centromedian thalamus for treatment of intractable Tourette syndrome — Anand V. Germanwala, Chloe Verducci, et al. · Surgical Neurology International (2025) | TGRS Research Map | TGRS