Diffuse midline H3K27-altered glioma in an atypical location mimicking a medulloblastoma
This case highlights the importance of considering DMG, particularly with H3K27 alterations, as a differential diagnosis in posterior fossa tumors. The presence of these genetic mutations significantly impacts both treatment decisions and prognosis. The variability in clinical presentation and tumor morphology associated with DMG underscores the need for thorough evaluation to optimize treatment strategies and further our understanding of this complex entity.
Authors
- Diego F. Sánchez (ORCID: https://orcid.org/0000-0002-9503-1947)
- Romina Argañaraz (ORCID: https://orcid.org/0000-0002-2528-2687)
- Yamila Basilotta Márquez (ORCID: https://orcid.org/0000-0003-0220-1722)
- Juan Francisco Medina Gallardo (ORCID: https://orcid.org/0000-0001-5400-1592)
Institutions
- Garrahan Hospital (AR)
Publication Details
- Journal
- Surgical Neurology International
- Published
- 2025-05-30
- DOI
- https://doi.org/10.25259/sni_238_2025
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00