NAT10 inhibits the pyroptosis of laryngeal squamous cell carcinoma through ac4C modification of ELANE mRNA
NAT10 inhibited the pyroptosis of LSCC cells and contributed to LSCC progression by suppressing ELANE mRNA stability in ac4C modification manner, indicating that the NAT10-ac4C-ELANE axis might be a potential target for LSCC.
Authors
- Jianwen Yan (ORCID: https://orcid.org/0000-0001-9898-5837)
- Yafang Yu (ORCID: https://orcid.org/0000-0002-7236-7798)
Institutions
- Fujian Medical University (CN)
- Fuzhou Second Hospital (CN)
- Union Hospital (US)
- Union Hospital (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1186/s12885-025-14352-0
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00