A phase I/IIa trial of atorvastatin in Japanese patients with acute Kawasaki disease and coronary artery aneurysms

We found that atorvastatin was safe and a dose up to 0.5 mg/kg/day for 6 weeks was well-tolerated in Japanese children with acute KD and CAAs.

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Publication Details

Journal
Pediatrics International
Published
2025-01-01
DOI
https://doi.org/10.1111/ped.70104
Primary Topic
Kawasaki Disease and Coronary Complications
Type
article
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article

A phase I/IIa trial of atorvastatin in Japanese patients with acute Kawasaki disease and coronary artery aneurysms

Shoko Imai, Ken‐Ichi Imadome, Kensuke Shoji, Adriana H. Tremoulet et al.
Pediatrics International
Kawasaki Disease and Coronary Complications
article

A phase I/IIa trial of atorvastatin in Japanese patients with acute Kawasaki disease and coronary artery aneurysms

Shoko Imai, Ken‐Ichi Imadome, Kensuke Shoji, Adriana H. Tremoulet, Shinobu Kobayashi, Eisuke Suganuma, Kenji Furuno, Zenpei Kano, Jane C. Burns, Chisato Shimizu, Hiroshi Masuda, Jumpei Saito
article en

Abstract

We found that atorvastatin was safe and a dose up to 0.5 mg/kg/day for 6 weeks was well-tolerated in Japanese children with acute KD and CAAs.

Pediatrics InternationalVol. 67(1)
Jichi Medical University (JP), University of California San Diego (US), Saitama Children's Medical Center (JP), Fukuoka Children's Hospital and Medical Center for Infectious Diseases (JP), Japanese Red Cross Fukuoka Hospital (JP), National Center For Child Health and Development (JP)
Good health and well-being
Openalex Percentile: Top 79%
Kawasaki Disease and Coronary Complications
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A phase I/IIa trial of atorvastatin in Japanese patients with acute Kawasaki disease and coronary artery aneurysms — Shoko Imai, Ken‐Ichi Imadome, et al. · Pediatrics International (2025) | TGRS Research Map | TGRS