Exploration of copy number variations and candidate genes in fetal congenital heart disease using chromosomal microarray analysis
The rates of chromosomal aneuploidy and CNV abnormalities in CHD cases with extracardiac anomalies were significantly higher than in the other two groups. Maternal age was not associated with the chromosomal abnormalities observed in CHD cases. KEGG pathway analysis indicated more intricate molecular pathways in complex CHD.
Authors
- Di Yao (ORCID: https://orcid.org/0000-0001-5262-7030)
- Yang Lan (ORCID: https://orcid.org/0000-0002-6231-9717)
- Hehua Tao (ORCID: https://orcid.org/0000-0003-2841-7302)
- Caiqin Guo
- Jiang Xu (ORCID: https://orcid.org/0000-0002-1139-4063)
- Nan Shi (ORCID: https://orcid.org/0009-0001-0462-4027)
- Ruoshui Xia
Institutions
- Jiangnan University (CN)
Publication Details
- Journal
- Journal of Perinatal Medicine
- Published
- 2025-05-29
- DOI
- https://doi.org/10.1515/jpm-2024-0599
- Citations
- 2
- Primary Topic
- Prenatal Screening and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 6.99
Funders
- Jiangnan University