A Comprehensive Evaluation of Clinicopathologic Characteristics, Molecular Features and Prognosis in Lung Adenocarcinoma with an Acinar Component

While the predominant pattern primarily dictates prognosis in LAUD, the presence of an acinar minor component alongside other high-grade patterns may further worsen outcomes. This underscores the necessity of considering the broader histological landscape rather than focusing solely on predominant patterns, as our findings show that minor acinar components can impact RFS alongside other histological patterns.

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Publication Details

Journal
Cancers
Published
2025-05-30
DOI
https://doi.org/10.3390/cancers17111825
Primary Topic
Lung Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

A Comprehensive Evaluation of Clinicopathologic Characteristics, Molecular Features and Prognosis in Lung Adenocarcinoma with an Acinar Component

Andréanne Gagné, Fabien C. Lamaze, Hanie Abolfathi, Dominique K. Boudreau et al.
Cancers
Lung Cancer Diagnosis and Treatment
article

A Comprehensive Evaluation of Clinicopathologic Characteristics, Molecular Features and Prognosis in Lung Adenocarcinoma with an Acinar Component

Andréanne Gagné, Fabien C. Lamaze, Hanie Abolfathi, Dominique K. Boudreau, Pierre Fiset, Victoria Saavedra Armero, Patrice Desmeules, Manal Kordahi, Michèle Orain, Yohan Bossé, Nathalie Gaudreault, Philippe Joubert
article en

Abstract

While the predominant pattern primarily dictates prognosis in LAUD, the presence of an acinar minor component alongside other high-grade patterns may further worsen outcomes. This underscores the necessity of considering the broader histological landscape rather than focusing solely on predominant patterns, as our findings show that minor acinar components can impact RFS alongside other histological patterns.

CancersVol. 17(11)
Institut universitaire de cardiologie et de pneumologie de Québec (CA), Université Laval (CA), McGill University (CA)
Openalex Percentile: Top 79%
Lung Cancer Diagnosis and Treatment
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