Fenofibrate ameliorates LPS-induced cardiac injury through alleviation of ferroptosis
Our findings suggest that Feno has the potential to protect against LPS-induced cardiac injury through the alleviation of ferroptosis, offering a promising therapeutic strategy for septic cardiomyopathy. However, the study is limited by the use of a single animal model and the lack of translational data in humans.
Authors
- Juan Ren (ORCID: https://orcid.org/0000-0002-8455-8057)
- Mai Chen (ORCID: https://orcid.org/0009-0005-0143-0701)
- Shunming Zhu
- Pengchao Ma
- Jun Liang (ORCID: https://orcid.org/0000-0003-0848-5658)
Institutions
- Shihezi University (CN)
- Shanxi Medical University (CN)
- Xinjiang Production and Construction Corps (CN)
- Shaanxi Provincial People's Hospital (CN)
- Shanxi Provincial People’s Hospital (CN)
Publication Details
- Journal
- Immunopharmacology and Immunotoxicology
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1080/08923973.2025.2507126
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00