Determinants of urinary pesticide metabolite concentrations in school-aged children from rural Bogotá, Colombia
This study aimed to determine urine pesticide metabolite concentrations using liquid chromatography and investigate associated exposure factors in a rural area of Bogotá, Colombia. In 2019, 231 urine samples were collected from children aged 7 to 10. Urinary pesticide metabolite concentrations were measured, and a questionnaire was administered to the children's mothers to collect exposure-related data. Multiple linear regression with log10-transformed concentrations was utilized to identify factors influencing these concentrations. Thirteen pesticide metabolites were detected in urine samples. The highest concentrations were observed in chlorpyrifos (TCP= 1.48 median IQ (0.57-3.5)) and pyrimethanil (2.73 median IQ (4.56 7.67)). Log-10 transformed metabolites of chlorpyrifos and profenophos were positively associated with maternal pesticide use (β = 0.13, 95%CI 0.04-0.2) and (β: 0.16 95%CI 0.0-0.3), respectively. In conclusion, this study unveiled widespread exposure to multiple pesticides and determined that pesticide concentrations in urine samples were influenced by both para-occupational and environmental exposure factors among schoolchildren.
Authors
- John Alexander Benavides Piracón (ORCID: https://orcid.org/0000-0002-7632-0372)
- Berna van Wendel de Joode (ORCID: https://orcid.org/0000-0001-9699-5046)
- Diego Alejandro Riaño-Herrera (ORCID: https://orcid.org/0000-0003-0580-9004)
- Diana Angélica Varela‐Martínez (ORCID: https://orcid.org/0000-0003-1688-8983)
- Nancy Jeanet Molina Achury (ORCID: https://orcid.org/0000-0001-5205-405X)
- Mónica Alejandra Quintana-Cortés (ORCID: https://orcid.org/0000-0003-2007-4413)
- José A. Menezes‐Filho (ORCID: https://orcid.org/0000-0002-3191-4484)
- Thereza Christina Bahia Coelho (ORCID: https://orcid.org/0000-0003-4787-4103)
- Iris Andrea Moya Muñoz (ORCID: https://orcid.org/0000-0002-6848-6372)
- Christian Lindh (ORCID: https://orcid.org/0000-0001-7435-9890)
- David Hernández-Bonilla (ORCID: https://orcid.org/0000-0003-0539-8495)
- Margarita Hidalgo-Mojica
Institutions
- Lund University (SE)
- Universidad Nacional (CR)
- Universidade Estadual de Feira de Santana (BR)
- Universidad Nacional de Colombia (CO)
- Universidad EAN (CO)
- Secretaría de Salud de Bogotá (CO)
- Universidad del Rosario (CO)
Publication Details
- Journal
- Ciência & Saúde Coletiva
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1590/1413-81232025305.16992023
- Primary Topic
- Pesticide Exposure and Toxicity
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Ministério da Ciência, Tecnologia e Inovação