Impact of innate lymphoid cell type 2 in chronic lymphocytic leukemia on the function of treg and CD8+ T cells through IL-9
ILC2s affect CD8<sup>+</sup> T cells and Treg cells through IL-9, weakening the anti-tumor effects of CD8<sup>+</sup> T cells and enhancing the immunosuppressive effects of Treg cells, thereby contributing to CLL pathogenesis.
Authors
- Jianhua Qu (ORCID: https://orcid.org/0000-0002-8267-322X)
- Alimu Xierenguli (ORCID: https://orcid.org/0000-0003-4004-9442)
- Ruixue Yang
- Xuejiao Zeng
Institutions
- Xinjiang Medical University (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
- People's Hospital of Xinjiang Uygur Autonomous Region (CN)
- Xinjiang Uygur Autonomous Region Uygur Medicine Hospital (CN)
Publication Details
- Journal
- Cancer Immunology Immunotherapy
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1007/s00262-025-04082-4
- Citations
- 1
- Primary Topic
- IL-33, ST2, and ILC Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- National Natural Science Foundation of China