Evaluation of Function and Biochemical Parameters of Platelet Concentrates (<scp>PCs</scp>) Prepared From Blood Donors With a History of <scp>COVID</scp>‐19 During the Platelet Storage

PC from donors recently recovered from COVID-19 exhibited a decline in aggregation in response to both collagen and arachidonic acid; however, the reduction in arachidonic acid-induced aggregation was particularly significant, indicating a selective impairment in platelet function following infection. Biochemical markers did not show significant differences between groups. Further studies with larger cohorts and clinical efficacy assessments are essential to comprehensively evaluate the safety and effectiveness of transfusing PC from donors recently recovered from COVID-19.

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Publication Details

Journal
Journal of Clinical Laboratory Analysis
Published
2025-05-30
DOI
https://doi.org/10.1002/jcla.70062
Primary Topic
COVID-19 Clinical Research Studies
Type
article
Field-Weighted Citation Impact
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article

Evaluation of Function and Biochemical Parameters of Platelet Concentrates (PCs) Prepared From Blood Donors With a History of COVID‐19 During the Platelet Storage

Fatemeh Arastehnazar, Mohammad Reza Deyhim, Mohammad Hessam Rafiee, Amir Teimourpour et al.
Journal of Clinical Laboratory Analysis
COVID-19 Clinical Research Studies
article

Evaluation of Function and Biochemical Parameters of Platelet Concentrates (PCs) Prepared From Blood Donors With a History of COVID‐19 During the Platelet Storage

Fatemeh Arastehnazar, Mohammad Reza Deyhim, Mohammad Hessam Rafiee, Amir Teimourpour, Faezeh Ghasemi
article en

Abstract

PC from donors recently recovered from COVID-19 exhibited a decline in aggregation in response to both collagen and arachidonic acid; however, the reduction in arachidonic acid-induced aggregation was particularly significant, indicating a selective impairment in platelet function following infection. Biochemical markers did not show significant differences between groups. Further studies with larger cohorts and clinical efficacy assessments are essential to comprehensively evaluate the safety and effectiveness of transfusing PC from donors recently recovered from COVID-19.

Journal of Clinical Laboratory AnalysisVol. 39(14)
High Institute for Education and Research in Transfusion Medicine (IR)
Openalex Percentile: Top 84%
COVID-19 Clinical Research Studies
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