Molecular detection of hrHPV-induced high-grade squamous intraepithelial lesions of the cervix through a targeted RNA next generation sequencing assay
HPV-RNA-SEQ improves the detection of HSIL lesions and has the potential to complete and eventually replace current molecular approaches as a first-line test. Further performance evaluation remains to be done on larger and prospective cohorts.
Authors
- Yves-Édouard Herpe (ORCID: https://orcid.org/0000-0002-0570-0917)
- Philippe Pérot (ORCID: https://orcid.org/0000-0002-5194-8200)
- Nolwenn Marie Dheilly (ORCID: https://orcid.org/0000-0002-3675-5013)
- Étienne Brochot (ORCID: https://orcid.org/0000-0002-8677-6349)
- Fabrice Bouilloux
- Guillaume P. Leboucher (ORCID: https://orcid.org/0000-0002-1019-2152)
- Marc Éloit (ORCID: https://orcid.org/0000-0002-1853-7207)
- Denis Chatelain
- Bénédicte Rognon
- Elise Jacquemet (ORCID: https://orcid.org/0000-0001-7539-3011)
- Alexandre Douablin
- Julia Faillace Thiesen
- Florent Percher
- Pascal Campagne
Institutions
- Institut Pasteur (FR)
- École Nationale Vétérinaire d'Alfort (FR)
- Université Paris Cité (FR)
- Centre Hospitalier Universitaire Amiens-Picardie (FR)
- Systématique, adaptation, évolution (FR)
- Centre Hospitalier de La Rochelle (FR)
- La Rochelle Université (FR)
Publication Details
- Journal
- Molecular Medicine
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1186/s10020-025-01238-x
- Citations
- 1
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 1.35