Proteomic Comparison of Conditioned Media from Mesenchymal Stem Cells of Different Human Tissues: Implications for Therapy

MSC-CMs from different tissues exhibit distinct protein profiles, while sharing common ECM signatures. These findings suggest that MSC-CM could be used for specific applications such as neurodegenerative diseases and wound healing, depending on the tissue source. Further in vivo research is needed to explore their clinical relevance.

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Publication Details

Journal
Journal of Stem Cells and Regenerative Medicine
Published
2025-05-30
DOI
https://doi.org/10.46582/jsrm.2101005
Primary Topic
Mesenchymal stem cell research
Type
article
Field-Weighted Citation Impact
0.00
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article

Proteomic Comparison of Conditioned Media from Mesenchymal Stem Cells of Different Human Tissues: Implications for Therapy

Tatsuya Sekine, Tsubasa Takane, Atsushi Terunuma, Yoshitaka Sekine et al.
Journal of Stem Cells and Regenerative Medicine
Mesenchymal stem cell research
article

Proteomic Comparison of Conditioned Media from Mesenchymal Stem Cells of Different Human Tissues: Implications for Therapy

Tatsuya Sekine, Tsubasa Takane, Atsushi Terunuma, Yoshitaka Sekine, Chen‐Yuan Chiu, Keisuke Ashiba, Hiroshi Terunuma
article en

Abstract

MSC-CMs from different tissues exhibit distinct protein profiles, while sharing common ECM signatures. These findings suggest that MSC-CM could be used for specific applications such as neurodegenerative diseases and wound healing, depending on the tissue source. Further in vivo research is needed to explore their clinical relevance.

Journal of Stem Cells and Regenerative MedicineVol. 21(1)
Biotherapy Institute of Japan (JP), Yotsuya Medical Cube (JP)
Zero hunger
Openalex Percentile: Top 82%
Mesenchymal stem cell research
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