Natural Selection as the Primary Driver of Codon Usage Bias in the Mitochondrial Genomes of Three Medicago Species

This study provides insights into the mitochondrial codon usage patterns and their evolutionary determinants in Medicago species, highlighting the predominant role of natural selection in shaping codon usage bias. The findings offer a foundation for comparative genomic studies and evolutionary analyses and may be beneficial for improving genetic engineering and breeding programs of <i>Medicago</i> species.