Histopathological image based breast cancer diagnosis using deep learning and bio inspired optimization

Breast cancer diagnosis remains a crucial challenge in medical research, necessitating accurate and automated detection methods. This study introduces an advanced deep learning framework for histopathological image classification, integrating AlexNet and Gated Recurrent Unit (GRU) networks, optimized using the Hippopotamus Optimization Algorithm (HOA). Initially, DenseNet-41 extracts intricate spatial features from histopathological images. These features are then processed by the hybrid AlexNet-GRU model, leveraging AlexNet's robust feature extraction and GRU's sequential learning capabilities. HOA is employed to fine-tune hyperparameters, ensuring optimal model performance. The proposed approach is evaluated on benchmark datasets (BreakHis and BACH), achieving a classification accuracy of 99.60%, surpassing existing state-of-the-art models. The results demonstrate the efficacy of integrating deep learning with bio-inspired optimization techniques in breast cancer detection. This research offers a robust and computationally efficient framework for improving early diagnosis and clinical decision-making, potentially enhancing patient outcomes.

Authors

Institutions

Publication Details

Journal
Scientific Reports
Published
2025-05-30
DOI
https://doi.org/10.1038/s41598-025-04136-8
Citations
11
Primary Topic
AI in cancer detection
Type
article
Field-Weighted Citation Impact
27.29
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Histopathological image based breast cancer diagnosis using deep learning and bio inspired optimization

Gaddam Venu Gopal, D. Pramodh Krishna, Kranthi Kumar Lella, Udayaraju Pamula et al.
11 citations
Scientific Reports
AI in cancer detection
27.29
article

Histopathological image based breast cancer diagnosis using deep learning and bio inspired optimization

Gaddam Venu Gopal, D. Pramodh Krishna, Kranthi Kumar Lella, Udayaraju Pamula, M. Ganesh Karthik, Venkata Nagaraju Thatha, S. Venkataramana
article en
11 citations

Abstract

Breast cancer diagnosis remains a crucial challenge in medical research, necessitating accurate and automated detection methods. This study introduces an advanced deep learning framework for histopathological image classification, integrating AlexNet and Gated Recurrent Unit (GRU) networks, optimized using the Hippopotamus Optimization Algorithm (HOA). Initially, DenseNet-41 extracts intricate spatial features from histopathological images. These features are then processed by the hybrid AlexNet-GRU model, leveraging AlexNet's robust feature extraction and GRU's sequential learning capabilities. HOA is employed to fine-tune hyperparameters, ensuring optimal model performance. The proposed approach is evaluated on benchmark datasets (BreakHis and BACH), achieving a classification accuracy of 99.60%, surpassing existing state-of-the-art models. The results demonstrate the efficacy of integrating deep learning with bio-inspired optimization techniques in breast cancer detection. This research offers a robust and computationally efficient framework for improving early diagnosis and clinical decision-making, potentially enhancing patient outcomes.

Scientific ReportsVol. 15(1)
Nagpur Institute of Technology (IN), SRM University (IN), VIT-AP University, Vikram University (IN), Koneru Lakshmaiah Education Foundation (IN), GITAM University (IN)
Good health and well-being
Openalex Percentile: Top 1%
AI in cancer detection
27.29
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Histopathological image based breast cancer diagnosis using deep learning and bio inspired optimization — Gaddam Venu Gopal, D. Pramodh Krishna, et al. · Scientific Reports (2025) | TGRS Research Map | TGRS