Metagenomics Diagnosis of a Parvovirus B19-Associated Encephalomyelitis in an Epidemic Context

In the context of increasing parvovirus B19 (B19V) infections, we describe a case of B19V encephalomyelitis without any usually associated clinical features. Etiology was identified by metagenomics and confirmed by PCR and whole-genome sequencing. This case highlights the need to consider the diagnosis of B19V infection in patients presenting with neurological symptoms.

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Publication Details

Journal
The Pediatric Infectious Disease Journal
Published
2025-05-30
DOI
https://doi.org/10.1097/inf.0000000000004780
Primary Topic
Parvovirus B19 Infection Studies
Type
article
Field-Weighted Citation Impact
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article

Metagenomics Diagnosis of a Parvovirus B19-Associated Encephalomyelitis in an Epidemic Context

Aurélie Truffot, Pierre Cappy, Patrice Morand, Julien Andréani et al.
The Pediatric Infectious Disease Journal
Parvovirus B19 Infection Studies
article

Metagenomics Diagnosis of a Parvovirus B19-Associated Encephalomyelitis in an Epidemic Context

Aurélie Truffot, Pierre Cappy, Patrice Morand, Julien Andréani, Hugo Jardin, Julien Lupo, Sylvie Larrat, Mina Smiljkovic, Julie Arata-Bardet, Christophe Rodriguez, Raphaële Germi, Elodie Lametery, Syrine Khedimallah, Noémie Court
article en

Abstract

In the context of increasing parvovirus B19 (B19V) infections, we describe a case of B19V encephalomyelitis without any usually associated clinical features. Etiology was identified by metagenomics and confirmed by PCR and whole-genome sequencing. This case highlights the need to consider the diagnosis of B19V infection in patients presenting with neurological symptoms.

The Pediatric Infectious Disease JournalVol. 44(7)
Centre National de la Recherche Scientifique (FR), Inserm (FR), Université Paris-Est Créteil (FR), Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR), Paris-Est Sup (FR), Centre Hospitalier Universitaire de Grenoble (FR), CEA Grenoble (FR), Assistance Publique – Hôpitaux de Paris (FR), Institut de Biologie Structurale (FR), Université Grenoble Alpes (FR)
Good health and well-being
Openalex Percentile: Top 84%
Parvovirus B19 Infection Studies
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