Short‐ and Long‐Term Effect of Multidomain Lifestyle Intervention on Frailty: Post Hoc Analysis of an <scp>RCT</scp>
A 2-year multimodal lifestyle intervention effectively prevented phenotypic pre-frailty/frailty, with sustained benefits observed up to 7 years. Continuous support for a healthy lifestyle may be necessary to prevent late-life pre-frailty or frailty.
Authors
- Jenni Lehtisalo (ORCID: https://orcid.org/0000-0002-8818-0848)
- Miia Kivipelto (ORCID: https://orcid.org/0000-0003-0992-3875)
- Tiia Ngandu (ORCID: https://orcid.org/0000-0002-3698-2021)
- Timo Strandberg (ORCID: https://orcid.org/0000-0001-6299-925X)
- Hanna‐Maria Roitto (ORCID: https://orcid.org/0000-0002-5466-2873)
- Esko Levälahti
- Jenni Kulmala (ORCID: https://orcid.org/0000-0003-0194-5551)
- Jaakko Tuomilehto (ORCID: https://orcid.org/0000-0002-3424-0745)
- Tiina Laatikainen
- Hilkka Soininen
- Riitta Antikainen
- Johanna Pöyhönen (ORCID: https://orcid.org/0009-0003-1524-6134)
Institutions
- Karolinska University Hospital (SE)
- University of Helsinki (FI)
- Tampere University (FI)
- Seinäjoki University of Applied Sciences (FI)
- University of Eastern Finland (FI)
- Oulu University Hospital (FI)
- Helsinki University Hospital (FI)
- Karolinska Institutet (SE)
- Karelia University of Applied Sciences (FI)
- Finnish Institute for Health and Welfare (FI)
- Escuela Nacional de Sanidad (ES)
- North Karelia Central Hospital (FI)
- Kuopio University Hospital (FI)
- Imperial College London (GB)
- University of Oulu (FI)
Publication Details
- Journal
- Journal of the American Geriatrics Society
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1111/jgs.19552
- Citations
- 5
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 6.12
Funders
- Yrjö Jahnssonin Säätiö
- Kela
- Suomen Kulttuurirahasto
- Opetus- ja Kulttuuriministeriö
- Hjärnfonden
- Juho Vainion Säätiö
- Päivikki ja Sakari Sohlbergin Säätiö
- Vetenskapsrådet
- NordForsk
- Norges Forskningsråd
- Sydäntutkimussäätiö
- Sigrid Juséliuksen Säätiö
- Forskningsrådet om Hälsa, Arbetsliv och Välfärd
- Alzheimerfonden
- Terveyden ja hyvinvoinnin laitos
- Center for Innovative Medicine