Soil‐Transmitted Helminths and the Intricacies of Immunoregulation: Evidence From Amazonian Ecuador for the Importance of Considering Species‐Specific Effects Within the Old Friends Hypothesis
Immune biomarkers varied by infection status: Ascaris infection may downregulate and Trichuris infection may exacerbate systemic inflammation. These preliminary findings suggest that STH species must be considered separately within the OFH.
Authors
- Tara J. Cepon‐Robins (ORCID: https://orcid.org/0000-0002-4508-8507)
- J. Josh Snodgrass
- Samuel S. Urlacher (ORCID: https://orcid.org/0000-0002-6489-4117)
- Geeta N. Eick (ORCID: https://orcid.org/0000-0001-7512-3265)
- Lawrence S. Sugiyama (ORCID: https://orcid.org/0000-0003-1279-0006)
- Felicia C. Madimenos (ORCID: https://orcid.org/0000-0001-5442-232X)
- Theresa E. Gildner (ORCID: https://orcid.org/0000-0001-7486-5208)
- Christopher J. Harrington (ORCID: https://orcid.org/0000-0003-0418-5770)
- Richard G. Bribiescas (ORCID: https://orcid.org/0000-0002-8228-307X)
- Melissa A. Liebert (ORCID: https://orcid.org/0000-0001-8013-6773)
Institutions
- Queens College, CUNY (US)
- Baylor University (US)
- University of Oregon (US)
- Northern Arizona University (US)
- Washington University in St. Louis (US)
- Hokkaido University (JP)
- Yale University (US)
- Center for Global Health (US)
- University of Colorado Colorado Springs (US)
Publication Details
- Journal
- American Journal of Human Biology
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1002/ajhb.70076
- Citations
- 4
- Primary Topic
- Parasite Biology and Host Interactions
- Type
- article
- Field-Weighted Citation Impact
- 6.87
Funders
- National Science Foundation
- Wenner-Gren Foundation
- Leakey Foundation
- University of Oregon
- National Institutes of Health