Differentiating Treatment‐Resistant Depression With and Without Parkinsonism in the Elderly From a Psychiatric Perspective by <sup>99m</sup>Tc‐TRODAT‐1 SPECT Imaging
Besides clinical assessment, dopaminergic assessment may help differentiate parkinsonism from TRD in old age. The findings of lower DAT availability in TRD suggest that TRD may be a prodromal symptom of Parkinson's disease. Psychiatrists should consider comorbid neurodegenerative disorders in elderly, depressed patients and use clinical assessment, neurological examination, and brain imaging for early Parkinson's Disease screening.
Authors
- Ren‐Shyan Liu
- Yu‐Hsien Chiu (ORCID: https://orcid.org/0000-0002-8233-4631)
- Li‐Fen Chen (ORCID: https://orcid.org/0000-0002-3819-853X)
- Chuncheng Huang
- Wei‐Chung Mao
- Tung‐Ping Su
Institutions
- National Yang Ming Chiao Tung University (TW)
- Cheng Hsin General Hospital (TW)
Publication Details
- Journal
- International Journal of Geriatric Psychiatry
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1002/gps.70102
- Primary Topic
- Parkinson's Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science and Technology Council