The UMPIRE study: A first‐in‐human multicenter trial of bilateral subscalp monitoring for epileptic seizure detection
This study demonstrates the safety and performance of the Minder bilateral subscalp EEG acquisition system for long-term seizure monitoring in patients with epilepsy. Bilateral hemisphere coverage captured seizures in a diverse patient group and permitted lateralization of events.
Authors
- Lisa Gillinder (ORCID: https://orcid.org/0000-0002-1909-4516)
- Michael Fong (ORCID: https://orcid.org/0000-0002-0874-7059)
- Taneeta M. Ganguly (ORCID: https://orcid.org/0000-0003-2390-868X)
- Karen McLean (ORCID: https://orcid.org/0000-0001-7833-1967)
- Aileen McGonigal (ORCID: https://orcid.org/0000-0001-6775-5318)
- Terence John O'Brien (ORCID: https://orcid.org/0000-0002-7198-8621)
- Piero Perucca (ORCID: https://orcid.org/0000-0002-7855-7066)
- Udaya Seneviratne (ORCID: https://orcid.org/0000-0003-0182-9702)
- Andrew J. Niemiec
- Joshua Laing (ORCID: https://orcid.org/0000-0001-8627-0690)
- Manori Wijayath
- Andrew Morokoff (ORCID: https://orcid.org/0000-0002-5159-3438)
- Robert Briggs (ORCID: https://orcid.org/0000-0001-9585-2692)
- Holly B. Fontenot (ORCID: https://orcid.org/0000-0002-7864-9171)
- Colin A. Ellis (ORCID: https://orcid.org/0000-0003-2152-8106)
- Erin C. Conrad (ORCID: https://orcid.org/0000-0001-8910-1817)
- Mark Cook (ORCID: https://orcid.org/0000-0002-8875-4135)
- Patrick Kwan (ORCID: https://orcid.org/0000-0001-7310-276X)
- Kristian Bulluss (ORCID: https://orcid.org/0000-0003-1465-1130)
- Alan Lai (ORCID: https://orcid.org/0000-0002-4825-0354)
- Ramya Raghupathi (ORCID: https://orcid.org/0009-0007-5080-5084)
- Wendyl D’Souza (ORCID: https://orcid.org/0000-0002-1750-5131)
- Amy J. Halliday (ORCID: https://orcid.org/0000-0001-6032-4347)
- Douglas E. Crompton (ORCID: https://orcid.org/0000-0002-0776-1203)
- Tracy Cameron (ORCID: https://orcid.org/0000-0003-3688-3813)
- Michael A. Murphy (ORCID: https://orcid.org/0000-0003-4630-0829)
- Jason Papacostas
- Matthew Gutman
- Andrew G. Lee (ORCID: https://orcid.org/0000-0002-5899-2239)
Institutions
- The University of Sydney (AU)
- Mater Health Services (AU)
- The Royal Melbourne Hospital (AU)
- The University of Queensland (AU)
- The University of Melbourne (AU)
- Northern Health (AU)
- Monash Medical Centre (AU)
- Princess Alexandra Hospital (AU)
- The Alfred Hospital (AU)
- Flinders Medical Centre (AU)
- Westmead Hospital (AU)
- St Vincent's Hospital Melbourne (AU)
- The Royal Victorian Eye & Ear Hospital (AU)
- Mater Research (AU)
- Agriculture Victoria (AU)
- Mater Adult Hospital (AU)
- Alfred Health (AU)
- Austin Health (AU)
- Monash University (AU)
- University of Pennsylvania (US)
Publication Details
- Journal
- Epilepsia
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1111/epi.18458
- Citations
- 14
- Primary Topic
- EEG and Brain-Computer Interfaces
- Type
- article
- Field-Weighted Citation Impact
- 20.04
Funders
- State Government of Victoria
- St Vincent's Hospital Melbourne