Innovative Application of a Rigidizing Overtube in Endoscopic Ultrasound–Guided Biopsy for Sampling of a Cecal Submucosal Lesion

Subepithelial lesions in the gastrointestinal tract present diagnostic challenges, particularly in difficult-to-access regions like the cecum. This case report describes a 71-year-old woman with a submucosal lesion adjacent to the appendix, where a rigidizing overtube was used to stabilize the colonoscope for an endoscopic ultrasound-guided fine-needle biopsy. The procedure was successful, obtaining a benign diagnosis without the need for surgery. This case highlights the utility of rigidizing overtube technology in enhancing the accuracy and safety of endoscopic interventions for subepithelial lesions, particularly in anatomically challenging locations like the cecum.