TERT promoter methylation predicts overall survival, immune cell infiltration and response to immunotherapy in clear cell renal cell carcinoma
TERT promoter methylation is a promising predictive biomarker of immune cell infiltration, overall survival, clinicopathological characteristics and response to anti-PD1 immunotherapy treatment in clear cell renal cell carcinoma patients.
Authors
- Long Qian (ORCID: https://orcid.org/0000-0002-4892-6588)
- Shirong Ding (ORCID: https://orcid.org/0000-0003-2578-7826)
- Jiahao Meng (ORCID: https://orcid.org/0000-0003-0511-3365)
- Kun Ye (ORCID: https://orcid.org/0009-0006-8209-1090)
- Hongyu Gao (ORCID: https://orcid.org/0000-0001-8633-3604)
- Limeng Qu
- Yue Hong
- Wenjun Yi (ORCID: https://orcid.org/0000-0002-1665-9622)
- Xinyu Guan
Institutions
- Central South University (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- Clinical Epigenetics
- Published
- 2025-05-30
- DOI
- https://doi.org/10.1186/s13148-025-01897-x
- Citations
- 2
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- National Natural Science Foundation of China
- Central South University
- China Postdoctoral Science Foundation
- State Key Laboratory of Oncology in South China
- Xiangya Hospital, Central South University